Condition in kids with possible COVID-19 link being studied in Canada

Condition in kids with possible COVID-19 link being studied in Canada

Condition in kids with possible COVID-19 link being studied in Canada

British Columbia and Alberta have become the latest provinces in Canada to investigate cases of an unusual syndrome in children, which doctors around the world are studying to see if there’s a definitive link to COVID-19.

The Hospital for Sick Children in Toronto and Montreal’s Sainte-Justine Hospital are each examining 20 possible cases of Multisystem Inflammatory Syndrome in Children, or MIS-C.

Earlier this week, Alberta’s chief medical officer of health announced doctors are looking into one suspected case in the province, while British Columbia said it is investigating half a dozen cases.

“Because there isn’t really a definitive, one specific test that says, ‘yes, you have multisystem inflammatory syndrome’ or ‘you don’t,’ I don’t think that the cases themselves are 100 per cent clearly defined from children who might have some other type of infection,” said Dr. Jeremy Friedman, the associate chief of pediatrics at SickKids.

“It might take a little bit of time to really be absolutely certain about how many cases that are being investigated are actually truly related to COVID.”

Friedman’s team at the Toronto hospital have also been in contact with the study at Sainte-Justine run by Marie-Paule Morin, a pediatric rheumatologist.

This month, the U.S. Centers for Disease Control and Prevention issued an alert to doctors about MIS-C. The agency’s case definition includes current or recent COVID-19 infection or exposure to the virus, a fever of at least 38 C for at least 24 hours, severe illness requiring hospitalization, inflammatory markers in blood tests, and evidence of problems affecting at least two organs that could include the heart, kidneys, lungs, skin or nervous system.

The CDC said some children may have symptoms resembling Kawasaki disease, a rare condition that can cause swelling and heart problems.

In other parts of the world, the illness is also called Pediatric Inflammatory Multisystem Syndrome (PIMS).

Dr. Deena Hinshaw, Alberta’s chief medical officer of health, said Wednesday that while little is known about MIS-C, ”it seems to be more something that happens as a result of (a child’s) immune system going into overdrive after an infection and causing this inflammatory response in multiple organs.”

Hinshaw gave little information about the province’s first suspected case, other to say that the child is stable in hospital.

In Toronto, Friedman said one of the 20 children had to be admitted to an intensive care unit. All have responded well to treatment and have gone home.

There have been no reported deaths linked to MIS-C in Canada, but some children have died from the illness in New York, France and the United Kingdom.

Friedman said it is “highly suspicious” that there seems to be an increase in children presenting MIS-C symptoms about a month after the peak in the number of COVID-19 infections in their communities.

“That seems to be a consistent time that people are seeing this uptick,” he said.

But Friedman noted that none of the children at SickKids tested positive for an active coronavirus infection. His team has blood samples from each child that will then be tested for COVID-19 antibodies.

Although Health Canada has recently approved two serological tests, Friedman said he is waiting to hear from provincial experts on which one is most accurate.

The Canadian Paediatric Society recently published MIS-C guidelines for clinicians and caregivers and is tracking and studying the illness nationwide.

“This syndrome is still very new, and scientists and doctors are learning about it in real time,” the society said in an email Friday.

“The CPSP study will provide essential, timely information about how children are being affected, which children are at highest risk, and will enable us to adjust best practices for prevention and care based on evidence.”

Friedman said parents should be vigilant about signs of MIS-C, but they shouldn’t be alarmed since the numbers are low and the condition is treatable.

“This is definitely going to add to what we know about COVID and hopefully some aspects of what we learn will inform the development of vaccines,” he said.

“It’s quite reassuring to know that we can all learn from each other and that is happens in a pretty rapid sequence.”

This report by The Canadian Press was first published May 29, 2020

— With files from The Associated Press

Daniela Germano, The Canadian Press

Coronavirus

Just Posted

Red Deer respiratory therapist Sarah MacKenzie was among the first central Alberta health professionals to receive the Pfizer vaccine in December 2020. Since then, nearly 3.4 million doses have been administered and COVID cases are falling rapidly. Photo by Alberta Health Services
Red Deer COVID cases continue to fall sharply

Red Deer cases almost into the double digits after topping more than 900 only five weeks ago

(Advocate file photo.)
Red Deer city council discusses strategies to restore integrated emergency dispatching

Red Deer city councillors discussed additional ways on Tuesday to try to… Continue reading

Local developers who are doing building upgrades or new construction will face less land servicing costs and gain some flexibility. (File photo by Advocate staff)
From left: Montana First Nation councillor Reggie Rabbit, Samson Cree Nation councillor Louise Omeasoo, Samson Cree Nation councillor Katherine Swampy, Samson Cree Nation councillor Shannon Buffalo and Samson Cree Nation chief Vern Saddleback were present during the painting of the Maskwacis Pride crosswalk. (Contributed photo)
Being gay made him contemplate suicide: Councillor in Maskwacis opens up

Maskwacis got a bit mote colourful over the weekend. Volunteers spent Saturday… Continue reading

Canadian Prime Minister Justin Trudeau participates in a plenary session at the G7 Summit in Carbis Bay, England on Friday June 11, 2021. THE CANADIAN PRESS/Adrian Wyld
Canada donating 13M surplus COVID-19 vaccine doses to poor countries

Trudeau says the government will pay for 87 million shots to be distributed to poor countries

Tampa Bay Lightning defenseman Jan Rutta (44) celebrates with defenseman Victor Hedman (77) after Rutta scored against the New York Islanders during the third period in Game 2 of an NHL hockey Stanley Cup semifinal playoff series Tuesday, June 15, 2021, in Tampa, Fla. (AP Photo/Chris O'Meara)
Kucherov shines, Lightning beat Islanders 4-2 in Game 2

Lightning 4 Islanders 2 (Series tied 2-2) TAMPA, Fla. — Brayden Point… Continue reading

Brooklyn Nets forward Kevin Durant (7) shoots as Milwaukee Bucks guard Pat Connaughton (24) defends during the fourth quarter of Game 5 of a second-round NBA basketball playoff series Tuesday, June 15, 2021, in New York. (AP Photo/Kathy Willens)
Durant’s sensational performance sends Nets to 3-2 lead

Nets 114 Bucks 108 (Brooklyn leads series 3-2) NEW YORK (AP) —… Continue reading

New York Yankees starting pitcher Jordan Montgomery throws to a Toronto Blue Jays batter during the first inning of a baseball game, Tuesday, June 15, 2021, in Buffalo, N.Y. (AP Photo/Jeffrey T. Barnes)
Frazier snaps tie, Yankees come back to beat Blue Jays 6-5

BUFFALO, N.Y. — Clint Frazier snapped an eighth-inning tie with a pinch-hit… Continue reading

The Pornhub website is shown on a computer screen in Toronto on Wednesday, Dec. 16, 2020. Pornhub says it has removed all content uploaded by non-verified users. The sex website faced accusations it hosted illegal content. The company, which is owned by Montreal-based Mindgeek, says it has suspended all previously uploaded content that was not created by one of its content partners or members of its Model Program. THE CANADIAN PRESS
International women’s rights advocates call on Canada to hold Pornhub to account

Jeanette Westbrook says being sexually abused as a child will haunt her… Continue reading

FILE - In this Jan. 9, 2021 file photo, transporters Miguel Lopez, right, Noe Meza prepare to move a body of a COVID-19 victim to a morgue at Providence Holy Cross Medical Center in the Mission Hills section of Los Angeles. The U.S. death toll from COVID-19 has topped 600,000, even as the vaccination drive has drastically slashed daily cases and deaths and allowed the country to emerge from the gloom. (AP Photo/Jae C. Hong, File)
US COVID-19 deaths hit 600,000, equal to yearly cancer toll

The U.S. death toll from COVID-19 topped 600,000 on Tuesday, even as… Continue reading

FILE - In this April 1, 2019 file photo, Louisiana Attorney General Jeff Landry talks about health care legislation he's backing in the upcoming session, in Baton Rouge, La. The Biden administration’s suspension of new oil and gas leases on federal land and water was blocked Tuesday by a federal judge in Louisiana. U.S. District Judge Terry Doughty's ruling came in a lawsuit filed in March by Louisiana’s Republican attorney general, Jeff Landry and officials in 12 other states. (AP Photo/Melinda Deslatte, File)
Federal judge blocks Biden’s pause on new oil, gas leases

NEW ORLEANS (AP) — The Biden administration’s suspension of new oil and… Continue reading

Israeli police officers detain a Palestinian man during clashes that erupted ahead of a planned march by Jewish ultranationalists through east Jerusalem, outside Jerusalem's Old City, Tuesday, June 15, 2021. (AP Photo/Mahmoud Illean)
Israelis march in east Jerusalem in test for new government

JERUSALEM (AP) — Hundreds of Israeli ultranationalists, some chanting “Death to Arabs,”… Continue reading

Montreal Canadiens right wing Brendan Gallagher (11) vies for the puck with Vegas Golden Knights defenseman Alex Pietrangelo (7) during the third period in Game 1 of an NHL hockey Stanley Cup semifinal playoff series Monday, June 14, 2021, in Las Vegas. (AP Photo/John Locher)
Vets Pietrangelo, Perry contributing for Vegas, Montreal

LAS VEGAS — Alex Pietrangelo and Corey Perry had very different free… Continue reading

Most Read